Frontiers Research Topic: Radiation-Induced Effects and the Immune System
نویسندگان
چکیده
delivery of macromolecules and other therapeutics to irradiated tumors. A major focus of this e-book is to elucidate immunological facets of ionizing irradiation. It is indeed becoming clear that highand low-dose irradiation elicit distinct immunological effects. Furthermore, the mode of irradiation-induced cell death (e.g., apoptosis, necrosis) has a major impact on anticancer immune responses. Overall, the e-book aims at review the current knowledge on the role of ionizing irradiation in antitumor immunity. This knowledge is instrumental for the development of innovative therapeutic modalities involving the combination of radio(chemo)therapy and immunotherapy in patients with locally advanced tumors.
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